Pyrosequencing technology has Built-in Quality Control

• The only rapid genotyping method that yields sequence data.
• QC is therefore a matter of reading the surrounding sequence.
• Every sample contains all the information required to validate it.

Alternative genotyping technologies report a fluorescent signal, or some form of yes/no answer. There is no simple procedure to identify a deviation.

Particularly in clinical research, deviations are as significant as predicted results. That´s why Pyrosequencing technology is the method of choice for identifying rapidly mutating organisms, e.g. in antibiotic resistance studies, since Pyrosequencing assays keep on working with unexpected genetic mutations.

Any level of expertise can confirm the integrity of the obtained data - it's as easy as reading text information. The output data from Pyrosequencing technology is the gold standard of genetic information: the sequence itself. This is the easiest information to share and communicate in the literature and with your research collaborators.