Using a 100 µL sample size, most of the tested analytes were recovered at 70 percent or greater. The analytical response for the extracted analytes with high matrix effects was sufficient to achieve adequate recoveries and LODs. This method, therefore, supports the use of ISOLUTE® SLE+ for the screening of urine samples for various illicit and prescribed drugs.
Codeine, hydrocodone, oxycodone, norcodeine, oxymorphone, 6-acetyl codeine, alprazolam, clonazepam, diazepam, flunitrazepam, nitrazepam, oxazepam, temazepam, dextromethorphan, buprenorphine, norbuprenorphine, fentanyl, EDDP, benzoylecgonine, tetrahydrocannabinol, normeperidine, naltrexone, hydromorphone, propoxyphene, pentazocine, amphetamine, norfentanyl, MDEA, butalbital, pentobarbital, phenobarbital, secobarbital, 11-nor-9 –carboxy- Δ9-tetrahydrocannabinol, and d3-11-hydroxy-tetrahydrocannabinol.
Download the application note below.
Thank you for visiting our Analytica Booth
Application Video: Extraction Steroids from Serum with ISOLUTE® SLE+
Biotage Industrial Flash Cartridges Explained
Finally - an Easy Urine Sample Preparation for LC/MS Analysis
A Smorgasbord of Analytical Methods