As medicinal chemistry broadens its scope beyond Lipinski’s rule of 5, compounds with more polar functionality and complexity are being created. Often, these compounds are too polar/ionizable for normal phase purification and therefore require reversed phase chromatography.
Though conventional 50 μm C18 media will often suffice, the increased molecular complexity usually needs more resolution to enable quality purification. This poster shows how the new high-performance reversed phase flash cartridge Biotage® SNAP Ultra C18 increases separation power and increases loading capacity 2x over conventional C18 cartridges.
Finally - an Easy Urine Sample Preparation for LC/MS Analysis
A Smorgasbord of Analytical Methods
Extraction of Acidic Catecholamine Metabolites in Plasma Using EVOLUTE® EXPRESS ABN Prior to LC-MS/MS Analysis
Seminar: An Introduction to the Biotage Automated Workflow Solution
The 2018 Analytical Catalog is Here