|Chemical description||Unmodified polystyrene-divinyl benzene copolymer|
|Average particle size||65 µm|
|Pore diameter||100 Å|
Analysis of the perfluorinated alkyl acids listed in EPA Method 537 along with fluorotelomeric alcohols and perfluorinated sulfonates were extracted using SPE (using ISOLUTE 101 500 mg/ 6 mL SDVB SPE columns) and analyzed on the LCMS 8045. Minimum Detection Limits(MDL) ranged from 0.69 to 3.25 ppt. Extraction recoveries were greater than 80% for all compounds, with surrogate recoveries within 10% of the true value.
Tags: Application Notes, Column, Drinking water, English, Environmental, LC-MS/MS, Polyfluorinated acids
This application note demonstrates an effective and efficient suported liquid extraction protocol for the clean up and concentration of a range of forensically significant opiates and their metabolites
ISOLUTE, unknown screening,
Tags: Acidic drugs, Application Notes, Basic drugs, Column, Forensic, Naphyrone, Post-Mortem fluids, Post-Mortem tissue
This method is suggested for the purification (de-salting) of aqueous peptide synthesis mixtures using ISOLUTE 101 non-polar columns. See General Comments for details on how this approach works.
Tags: Application Notes
This method is recommended for the extraction of oligonucleotides from aqueous synthesis mixtures using a non-polar retention mechanism. See General Comments for more details on how this works.
Tags: Application Notes
This method is suggested for the simultaneous extraction of acidic, neutral and basic compounds from postmortem tissues, blood and urine. The retention mechanism is hydrophobic.
Tags: Application Notes
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
Tags: Manuals & User Guides
This Chemistry Data Sheet includes specifics on the use of ISOLUTE 101 for the extraction of polar analytes from aqueous samples (page 1), ordering information (page 2) and a general discussion on non-polar sorbents (appendix page 3).
Tags: Product Notes
The Biotage 2018 catalog of analytical sample preparation products for chemistry professionals is now available. This edition includes a comprehensive range of sample preparation consumables for bi...17 July 2017
On July 1st, Biotage expanded its direct sales organization and opened the door to analytical customers in Italy. Account Manager Gianluca Pessoni is added to the Italian team, filling the ana...28 June 2017
This application note from Biotage Labs describes a method for extracting nitrosamines from urine. The ISOLUTE® SLE+ sample preparation method allows for a fast extraction with sufficient sampl...15 June 2017
This application note describes the extraction of amphetamine and amphetamine-style compounds from hair matrix prior to GC/MS analysis following bead homogenization. This application note describe...20 March 2017
This application note describes the operating conditions for the automated fractionation of EPH into aliphatic and PAH fractions using the ISOLUTE® EPH column in conjunction with the Biotage&re...20 February 2017
This application note describes the extraction of 49 drugs of abuse from whole blood, prior to UPLC-MS/MS analysis. An effective and efficient ISOLUTE SLE+ protocol optimized the for ...05 January 2016
Now available, the Biotage 2016 catalog of analytical sample preparation products for chemistry professionals. This edition includes a comprehensive range of products for bioanalysis, forensic, cli...11 August 2015
Dilute and shoot (D&S) methods are promoted for use by analytical instrument vendors in clinical, forensic toxicology and bioanalytical laboratories. More sensitive LC-MS/MS systems make this s...27 March 2015
Biotage, pioneers in flash chromatography, started packing columns with silica for flash purification 30 years ago. Some of the first employees are still with us today. In this video, site director...08 January 2015
Now available, the Biotage 2015 catalog of analytical sample preparation products for chemistry professionals. This edition includes a comprehensive range of products for bioanalysis, forensic, cli...29 July 2014
Buy your Biotage consumables through our website and shipping is free For a limited time, free shipping is applied to Biotage consumables orders through the Biotage website*. Let Biotage make orde...
What is the maximum capacity of an SPE column?
The capacity of a sorbent is defined as the total mass of strongly retained analyte that can be retained by a given mass of the sorbent under optimum conditions.
For most sorbents, this can range from 1-5% by weight. 100 mg of sorbent might retain 1-5 mg of analyte.
Ion exchange sorbents typically have a capacity of 0.3-1 meq/g.Browse more questions and answers >
|Part No.||Description||Product type||Pack Size||Price|
|101-0002-A||ISOLUTE® 101 25 mg/1 mL||Consumables||100||Log in for price|
|101-0010-B||ISOLUTE® 101 100 mg/3 mL||Consumables||50||Log in for price|
|101-0020-B||ISOLUTE® 101 200 mg/3 mL||Consumables||50||Log in for price|
||101-0020-C||ISOLUTE® 101 200 mg/6 mL||Consumables||30||Log in for price|
|101-0050-B||ISOLUTE® 101 500 mg/3 mL||Consumables||50||Log in for price|
||101-0050-C||ISOLUTE® 101 500 mg/6 mL||Consumables||30||Log in for price|