EVOLUTE® EXPRESS Solid Phase Extraction products
from Biotage are designed for all your sample
preparation challenges. Whether you are working in the field of bio-analysis during drug development, clinical or forensic
toxicology, or with the diversity of samples in food
safety and environmental applications, the tools and
methods used for sample preparation have a clear
impact on productivity. This user guide contains information about choosing the correct EVOLUTE EXPRESS product for your application and optimizing your methodology for best results.
Part No: P200Issued year: 2019File size: 2.44mbFile type: pdf
Sample preparation is generally regarded as a pain point for many labs as it can be laborious, time consuming and relatively expensive. In a high throughput setting performing offline chemistry also leads to increases in sample turnaround time and reporting.
This poster evaluates simplified sample preparation workflows using optimized sample hold-up technology allowing chemistry in-situ. Reduced labour, extraction complexity, processing time, solvent usage and resultant instrument contamination and downtime can offset upfront costs associated with sample preparation.
Part No: TN-0012.0610Issued year: 2010File size: 0.38mbFile type: pdf
Through innovative patented technology molecularly
imprinted polymers (MIPs) can afford improved clean-up in
your processes. Unwanted contaminants or high value
desirables can be efficiently extracted from processes
streams, resulting in more efficient production and cleaner
Part No: AN717Issued year: 2010File size: 0.48mbFile type: pdf
Pharmaceutical companies and those who supply them with intermediates, constantly strive to produce API’s and
intermediates of the highest purity. At the same time, many established production facilities face strong competitive
pressures to produce high quality product at lower costs. Drug substance impurities are wide-ranging as described in the
International Conference on Harmonization (ICH) “Impurities in new Drug Substances”1. Of particular concern in recent
years are the ‘genotoxic compounds.
Part No: P128v2Issued year: 2016File size: 0.4mbFile type: pdf
This poster discusses various stages of the sample preparation process to determine and assess the potential for cross contamination and present approaches to minimize and or eliminate the effect.
Part No: AN085-HORIssued year: 2013File size: 2.07mbFile type: pdf
The data given in this Application Note illustrates the fact that the combination of the Biotage(R) Horizon SmartPrep Automated Extractor, DryVap Concentrator, and DryDisk Separation Membranes represent a complete solution to the preparation of samples for the extraction of semi-volatile organics by EPA Method 525.3.
Part No: AN107-HORIssued year: 2016File size: 1.59mbFile type: pdf
China has set ambitious goals for cleanup and monitoring of drinking water. Methods that are rugged and sensitive are required to support this effort. Chinese Environmental Agency method SL 392-2007 has been developed for this purpose and specifies a C18 cartridge for extraction and GC/MS for the detection step.
Part No: AN715Issued year: 2011File size: 0.13mbFile type: pdf
This method demonstrates the extraction of a PAH standard test mix comprising of fluoranthene, benzo(a)anthracene, chrysene, benzo(b)fluoranthene, benzo(k)fluoranthene, benzo(a)pyrene, indeno(123-cd)pyrene, dibenzo(ah)anthracene, and benzo(ghi)perylene.
MIP, AFFINILUTE, SupelMIP, BIOTAGE, PAH, Polyaromatic Hydrocarbons
Part No: P209Issued year: 2019File size: 1.25mbFile type: pdf
this poster compares different extraction techniques (mixed-mode SPE: ISOLUTE HCX and EVOLUTE EXPRESS CX; Dual mode extraction (ISOLUTE HYDRO DME+) and supported liquid extraction (ISOLUTE SLE+)) for extraction of fentanyl and fentanyl analogues from both urine and whole blood.
Part No: AN833Issued year: 2015File size: 1.33mbFile type: pdf
This application note describes a polymer based-based weak exchange mixed-mode SPE protocol for the extraction of the aminoglycoside antibiotics gentamicin, streptomycin, spectinomycin and neomycin from chicken meat prior to LC-MS/MS analysis. Linearity and LOQ meet USDA-FSIS guidelines.
Part No: P120Issued year: 2015File size: 0.63mbFile type: pdf
This poster describes a comparison of 25-hydroxy Vitamin D Extraction using Supported Liquid Extraction and Phospholipid Depletion Plate Technology using Manual and Automated Sample Preparation prior to LC/MS Analysis. It was presented at MSACL 2015, San Diego
Part No: AN778Issued year: 2013File size: 0.88mbFile type: pdf
This methodology has been designed to give an effective and efficient supported liquid extraction protocol for the clean-up and concentration of salivary cortisol levels. Cortisol is a steroid hormone that when measured from saliva can be used as an indication of stress. Analyte recoveries achieved using this method ranged from 96-99% with RSDs below 3% (n=7) for all analytes.
Cortisol, Saliva, SLE, Supported Liquid Extraction, ISOLUTE, Clinical, Steroid Hormones, Stress
Part No: AN777Issued year: 2013File size: 0.86mbFile type: pdf
Cortisol is a steroid hormone that in urine can be used to diagnose hyper or hypo cortisol diseases such as Cushing’s Syndrome. This methodology has been designed to give an effective and efficient supported liquid extraction protocol for the clean-up and concentration of urinary cortisol levels. Analyte recoveries achieved using this method ranged from 99-101% with RSDs below 5% for all analytes.
Cortisol, Steroid hormone, Cushing's Syndrome, Cushing's Disease, Clinical, SLE, Supported Liquid Extraction, Stress,