Part No: IST1014SIssued year: 2005File size: 0.03mbFile type: pdf
This represents recommendations for SPE method development. The proposed steps are
based on experience with similar analytes and matrices, but have not been verified in
Biotage laboratories. Please refer to section below for the analyte and matrix
considerations that were made in developing this method. As for all method development, this procedure should first be developed using pure solvent spiked with analyte. Only after the chemistry is established should spiked matrix samples be tested.
Part No: IST1086SIssued year: 2006File size: 0.03mbFile type: pdf
The following method describes the extraction and separation of non-conjugated parent, glucuronide conjugates and sulfate conjugates of a proprietary pharmaceutical from urine and bile using non-polar and anion exchange mechanisms.