Aflatoxins, a mold largely produced by Aspergillus flavus and Aspergillus parasiticus1 are commonly tested mycotoxins found naturally in a wide range of agriculture crops and food products. Due to their harmful effects on human health, animal health, and global trade, aflatoxins are regulated in most countries and have established global limits in a wide variety of matrices.

Aflatoxin B1 Aflatoxin B2 Aflatoxin G1 Aflatoxin G2 Application Notes Column English Food Food HPLC Mycotoxin

The compound 4-methylimidazole (4-MEI) is formed as a byproduct in some foods and beverages. Caramel coloring Type III and Type IV in beverages is one of the ingredients which may contain 4-MEI. Products that potentially contain 4-MEI include certain colas, beers, soy sauces, breads, coffee, ammoniated livestock feed and other products.

4-Methylimidazole (4-MEI) Application Notes Food Food Food Additives Food Colours LC-MS/MS SmartPrep

Mycotoxin testing awareness has increased as countries involved in world trade of raw agriculture and processed consumer products rely on a safe global food supply. Several mycotoxins are naturally produced and monitored; however, aflatoxins, produced mainly by the Aspergillus species, are considered to be the most important mycotoxin group in the world’s food supply to monitor.

Aflatoxin B1 Aflatoxin B2 Aflatoxin G1 Aflatoxin G2 Application Notes English Food Food Mycotoxin SmartPrep

Polychlorinated biphenyls (PCBs) are found throughout the environment and are recognized as a serious health threat. They accumulate in animals and plants and become more concentrated as they progress up the food chain. PCBs can be found in the fatty tissues of human populations in all industrial countries, and they can be passed from mother to fetus through the placenta and to an infant through breast milk. They have been introduced into the environment mainly through the use of Aroclor products.

Application Notes English Environmental Food GC-MS PCBs

Deoxynivalenol is a common mycotoxin found in agricultural grain crops and final consumer processed products. Most impacted are wheat, barley, and corn. Deoxynivalenol, also known as Vomitoxin, is produced by Fusarium fungi and has a unique dual-stage growth cycle of producing mold during warm daylight and toxin during cool nights. There is no known procedure or processing that will remove deoxynivalenol that is already present in grain.

Application Notes Deoxynivalenol (DON) English Food Food Mycotoxin SmartPrep

Mycotoxin testing in consumer food products has become increasingly important as global food trade increases, making it necessary to identify mycotoxins efficiently and accurately. Deoxynivalenol, also known as vomitoxin, is a mycotoxin commonly found in wheat feed crops. Because wheat is a highly-used raw agricultural export commodity in many counties for both animal feed and consumer food products, it is an important component in the diets of both humans and animals.

Application Notes Deoxynivalenol (DON) English Food Food HPLC Mycotoxin SmartPrep

This method describes the clean-up of acrylamide from cooked foodstuffs, using a multimode retention mechanism (hydrophobic, cation and anion exchange) for retention of interfering food components. The analytical technique is LC-MS-MS. ISOLUTE, MULTIMODE, SPE, FOOD, FOOD SCARE

Acrylamide Application Notes Column Food Food Food contaminant LC-MS/MS

Malachite green (MG) and crystal (gentian) violet (CV) are triphenylmethane dyes used in aquaculture as fungicides and ectoparasiticides. They are rapidly metabolised to the leucomalachite green (LMG) and leucocrystal (gentian) violet (LCV) metabolites that persist in fish tissue. MG and CV are banned in many countries due to their mutagenicity and carcinogenicity, but may still be used illegally. Monitoring methodologies must be able to detect the compounds at 1 ng/g (US) or 2 ng/g (EU). In order to meet these LODs for complex matrices such as oily fish, and the low UV absorbance of the leuco forms, LC-MS-MS is the analytical method of choice. This application note focuses on ease of use when compared to other methods, and describes a QuEChERS based approach incorporating the use of aluminium oxide in enhanced dispersive SPE to reduce the levels of fat in the final extract. Additional cleanup is provided by polymeric EVOLUTE SPE columns, and the resulting extract demonstrated low ion suppression. Analyte recoveries of 60-105%, with low rsds, are achieved. The method is also applicable to Brilliant green. Malachite green, Leuco malachite green, Crystal violet, Leuco crystal violet, Brilliant Green, EVOLUTE, EVOLUTE CX, QuEChERS, LC/MS/MS, Salmon, Contamination, Gentian violet, SPE, Solid Phase Extraction, Polymer, Resin,

Application Notes Brilliant Green Column Crystal Violet Fish Food Food Gentian Violet LC-MS/MS Leuco Crystal Violet Leuco Malachite Green Malachite Green Salmon Triphenylmethane Dyes Veterinary drugs

This application note was developed for the clean-up of a non-polar solvent extract of vegetable material. The methodology is applicable to a wide range of organochlorine and organophosphorus pesticides and a number of vegetable types. The analytes are relatively non-polar, and will not be strongly retained by polar/anion exchange sorbents.

Application Notes Clordane Column Dicofol Endosulfan Food Food GC-MS Organochlorines Organophosphate Pesticide Organophosphates Pesticides Vegetables

The United States Food & Drug Administration (FDA) regulates the approval of color additives for their safe use in foods, cosmetics, pharmaceuticals/drugs, and medical devices. The Federal Food, Drug, and Cosmetic Act (FD&C Act) contains provisions for what color additives are required to be certified. These provisions are monitored by the FDA, and through the Code of Federal Regulations (CFR), the FDA releases information on new color additives and new uses for certified color additives.

Application Notes English Food Food Food Additives Food Colours Food contaminant SmartPrep

SPE Application for the Multiresidue Extraction and Clean Up from Fruit and Vegetables. The method can be used for the extraction of a range of commodities (fresh fruits and vegetables) and is suitablefor analysis of organophosphorus, organochlorine and carbamate pesticide types, using a variety of appropriate analytical techniques.

Application Notes Food Food Vegetables