Analysis of the perfluorinated alkyl acids listed in EPA Method 537 along with fluorotelomeric alcohols and perfluorinated sulfonates were extracted using SPE (using ISOLUTE 101 500 mg/ 6 mL SDVB SPE columns) and analyzed on the LCMS 8045. Minimum Detection Limits(MDL) ranged from 0.69 to 3.25 ppt. Extraction recoveries were greater than 80% for all compounds, with surrogate recoveries within 10% of the true value.
This application note demonstrates an effective and efficient suported liquid extraction protocol for the clean up and concentration of a range of forensically significant opiates and their metabolites ISOLUTE, unknown screening,
This application note describes a method for the extraction of pesticides from environmental water samples using ISOLUTE® 101 solid phase extraction columns.
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
ISOLUTE 101, ENV+. Presented at 10 Symposium on Handling of Environmental and Biological Samples in Chromatography, April 2001, Mainz/Wiesbaden, Germany
Perfluorinated compounds (PFCs) are a group of compounds that have been used in a wide array of industrial and household applications, including fabric protectors, non-stick coatings for cookware, coatings for food packaging and in some fire-fighting foams. Their persistence in the environment allows them to accumulate in water sources, particularly those used for consumption. This work will demonstrate the use of a cartridge-based extraction system to extract and quantify up to 24 PFC compounds in drinking water to highlight the challenges associated with this application. APHL 2019