Shopping Cart (Login required)
Biotage cannabis SLE banner

Detecting Cannabis in Blood Samples

05 May 2015

Whole blood is an increasingly important matrix for forensic toxicology screening and confirmation applications. Supported liquid extraction using ISOLUTE® SLE+ is well suited to handling this sometimes difficult matrix.


This application note describes the extraction of Δ9-THC (tetrahydrocannabinol), 11-hydroxy- Δ9-THC and 11-nor-9-carboxy-THC from whole blood matrix, prior to GC/MS analysis. An extremely simple sample pre-treatment and extraction method is employed to extract the parent THC and main metabolites from complex whole blood matrix, delivering high, reproducible analyte recoveries. The optimized SLE+ protocol demonstrated analyte recoveries ranging from 72-83%. RSD’s were below 10% for all analytes.

Featured Videos

ISOLUTE® SLE+ Supported Liquid Extraction