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Fully Automated Analysis of Pharmaceuticals in Water

25 July 2016

This new application note describes the use of EVOLUTE® EXPRESS ABN on-line cartridges in a fully automated on-line SPE-LC-MS/MS method for extraction and quantification of 13 commonly prescribed pharmaceuticals (with a range of characteristics) in water.


Trace analysis of organics in water traditionally involves large sample volumes, labor intensive procedures and relatively high use of solvents. The on-line SPE approach uses a simple, well established hardware setup, and fully integrates sample preparation into the analytical workflow. Typical sample volumes of 1–10 mL, and lower solvent usage mean sample collection, transport and handling, along with solvent disposal costs, are much reduced.

Read more about how EVOLUTE® EXPRESS ABN on-line cartridges were used in the application note below:

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