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PPM-A48-1275
Collection Rack 12 X 75 mm, Biotage® PRESSURE+ 48
Read more on the product page
» APPLICATION NOTES
Practical Considerations using Quantisal Oral Fluid Collection Devices and SPE Method Development by Polymeric Mixed-Mode Cation Exchange
Oral fluid is of increasing importance as a biological
matrix in drugs of abuse and related analyte testing
because of the ease of sample collection, and
difficulty in adulteration of samples, particularly
when compared with urine.
Tags:
Application Notes,
Forensic
Sample Preparation of a Drugs of Abuse Panel in Human Hair Using ISOLUTE® SLE+ Prior to UPLC-MS/MS Analysis
This application note describes a procedure for sample
pre-treatment and extraction of a panel of 49 drugs of
abuse from human hair, using Biotage® Lysera for matrix
micropulverization, prior to clean up using ISOLUTE® SLE
supported liquid extraction. The application note contains
procedures optimized for 400 μL capacity column format and
200 μL and 400 μL supported liquid extraction plate formats,
for higher throughput applications. The methodology delivers
clean extracts and analyte recoveries mostly greater than
80% with RSDs lower than 10% for all analytes and LLOQ from
1 ng/mL.
Tags:
6-MAM,
7-Aminoclonazepam,
7-Aminoflunitrazepam,
96-well plate,
Alprazolam,
Amphetamine,
Application Notes,
Bromazepam,
Buprenorphine,
Clinical,
Clonazepam,
Cocaine,
Codeine,
Column,
Diazepam,
Dihydrocodeine (DHC),
Drugs of Abuse,
EDDP,
English,
Estazolam,
Fentanyl,
Flunitrazepam,
Flurazepam,
Hair,
Hydrocodone,
Hydromorphone,
Ketamine,
Lorazepam,
Lysergic acid diethylamide (LSD),
MDA,
MDMA,
Mephedrone,
Methadone,
Midazolam,
Morphine,
Nitrazepam,
Norbuprenorphine,
Nordiazepam,
Norfentanyl,
Norketamine,
Oxazepam,
Oxycodone,
Oxymorphone,
Phencyclidine (PCP),
Temazepam,
Triazolam,
UPLC-MS/MS,
Zaleplone,
Zolpidem,
Zopiclone,
α-OH alprazolam
Streamlined Sample Preparation of a Drugs of Abuse Panel in Human Hair Using ISOLUTE® SLE+ Prior to UPLC-MS/MS Analysis
This application note describes a streamlined procedure for
sample pre-treatment and extraction of a panel of 49 drugs
of abuse from human hair, using Biotage® Lysera for matrix
micropulverization, prior to direct transfer to clean up using
ISOLUTE® SLE supported liquid extraction.
Tags:
96-well plate,
Alprazolam,
Amphetamine,
Application Notes,
Bromazepam,
Buprenorphine,
Clinical,
Clonazepam,
Cocaine,
Codeine,
Column,
Diazepam,
Dihydrocodeine (DHC),
Drugs of Abuse,
EDDP,
English,
Estazolam,
Fentanyl,
Flunitrazepam,
Flurazepam,
Hair,
Hydrocodone,
Hydromorphone,
Ketamine,
Lorazepam,
Lysergic acid diethylamide (LSD),
MDA,
MDEA,
MDMA,
Mephedrone,
Methamphetamine,
Methedrone,
Midazolam,
Morphine,
Nitrazepam,
Norbuprenorphine,
Nordiazepam,
Norfentanyl,
Norketamine,
Oxazepam,
Oxycodone,
Oxymorphone,
PCB,
Temazepam,
Triazolam,
UPLC-MS/MS,
Zaleplone,
Zolpidem,
Zopiclone
How to Process ISOLUTE SLE+ Plates and Columns with Pressure+ 96 & 48 Positive Pressure Manifolds
Biotage® PRESSURE+ manifolds deliver positive pressure, parallel processing for 96 well plates and column formats. The systems utilize a consistent, uniform flow of positive pressure to move both low and high viscosity liquids through SPE plates and columns. ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and greatly matrix effects associated with biofluid analysis.
SLE+, SLE, Supported Liquid Extraction, positive pressure manifold, Pressure+96, Pressure+48
Tags:
Application Notes,
Aqueous,
Biological fluids,
Column,
Plasma,
Post-Mortem fluids,
Urine,
Water,
Whole blood
» CATALOGS
Analytical Sample Preparation 2019 Catalog
In this catalog product information is displayed with easy-to-follow application details and supporting documentation. Ordering information is found following each product listing.
Tags:
Catalogs
» CERTIFICATES
PRESSURE+ Declaration of Conformity
PRESSURE+ Declaration of Conformity
Tags:
Certificates
» MANUALS & USER GUIDES
» POSTERS
A fast effective sample cleanup method for applications related to food safety surveillance in the screening of commercial meat products for aminoglycoside residues
This poster details current sample preparation strategies for aminoglycoside antibiotics in meat developed in a collaborative effort with Biotage and Tyson Foods, Inc. Springdale Corporate Laboratory to optimize analyte recovery (>70%), minimize analyte suppression and maintain acceptable method precision.
FAST LC-MS 2014
Tags:
Aminoglycoside antibiotics,
Chicken meat,
Column,
English,
Food,
Gentamicin,
LC-MS/MS,
Neomycin,
Posters,
Spectinomycin,
Streptomycin,
Veterinary drugs
» PRODUCT NOTES
PRESSURE+48 and PRESSURE+96
Biotage® PRESSURE+ manifolds deliver positive pressure, parallel processing for 96 well plates,
1 mL 3 mL and 6 mL column formats. The systems utilize a consistent, uniform flow of positive pressure to move both low and high viscosity liquids through SPE plates and columns. Each port of the PRESSURE+ manifold independently maintains constant pressure, increasing the overall reproducibility of analyte recoveries. This unique design allows for partially populated racks to be used without sacrificing extraction efficiency.
Tags:
Product Notes
Search all documents »
PRODUCT VIDEOS
Biotage® PRESSURE+ 48 Manifold Demonstration
Biotage® PRESSURE+ 96 Manifold Demonstration
News
24 April 2019Hydrolyze Urine Samples In-Situ - New Application Note
This application note demonstrates the applicability of our newest sample preparation consumable, ISOLUTE® HYDRO DME+ for in-situ hydrolysis and clean-up of urine samples, for the analysis of a...
14 September 2018New Application Note for Simultaneous Extraction of Aldosterone and Angiotensin I and II from Human Plasma
Plasma renin activity (PRA) determination is used in the diagnosis of primary aldosteronism, an important cause of secondary hypertension (high blood pressure). Concomitant measurement of both aldo...
04 June 2018White Paper from Biotage: Practical Considerations Using Quantisal® Oral Fluid Collection Devices
Oral fluid is a popular matrix for drugs of abuse testing. It is easy to collect and more difficult to adulterate than urine. A new white paper from Biotage deals with practical considerations...
31 January 2018Extraction of Acidic Catecholamine Metabolites in Plasma Using EVOLUTE® EXPRESS ABN Prior to LC-MS/MS Analysis
This application note describes a solid phase extraction protocol for the extraction of three catecholamine metabolites (vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid) fro...
11 January 2018The 2018 Analytical Catalog is Here
The Biotage 2018 catalog of analytical sample preparation products for chemistry professionals is now available. This edition includes a comprehensive range of sample preparation consumables for bi...
17 July 2017Biotage Goes Direct in Italy
On July 1st, Biotage expanded its direct sales organization and opened the door to analytical customers in Italy. Account Manager Gianluca Pessoni is added to the Italian team, filling the ana...
19 May 2017Extraction of Oxytocin and Vasopressin from Serum Using EVOLUTE® EXPRESS ABN Prior to LC-MS/MS Analysis
The method described in this application note achieves high reproducible extraction recoveries of the peptides oxytocin and vasopressin from serum using a fast, simple EVOLUTE® EXPRESS Load-Was...
20 April 2017Extraction of Vitamin B7 (Biotin) from Serum Using EVOLUTE® EXPRESS ABN
Vitamin B7 (Biotin) is a water soluble vitamin necessary for cell growth. The method described in this application note achieves high reproducible extraction recoveries of vitamin B7 from serum whi...
15 February 2017Extraction of Benzodiazepines From Oral Fluid Using ISOLUTE® SLE+
This application note describes the extraction of benzodiazepine compounds from oral fluid matrix collected with the NeoSal™ devices, prior to GC/MS analysis. The protocol described ...
10 February 2017Extraction of Teicoplanin from Plasma Using EVOLUTE® EXPRESS ABN Prior to HPLC-DAD Analysis
The method described in this application from Biotage Labs demonstrates high, reproducible recovery of teicoplanin from human plasma. Samples were extracted using an EVOLUTE® EXPRESS ABN 30 mg ...
08 February 2017Extraction of Cocaine From Oral Fluid Using ISOLUTE® SLE+ After Collection With NeoSal™ Collection Device
This application note describes the extraction of cocaine and selected metabolites from oral fluid matrix following the collection with the NeoSal™ devices, prior to GC/MS analysis. ...
12 January 2017Extraction of Opiates from Oral Fluid Using ISOLUTE® SLE+
This application note describes the extraction of opiate compounds from oral fluid matrix collected using the NeoSal™ devices, prior to GC/MS analysis. This application note des...
08 January 20152015 Analytical Sample Preparation Catalog Released
Now available, the Biotage 2015 catalog of analytical sample preparation products for chemistry professionals. This edition includes a comprehensive range of products for bioanalysis, forensic, cli...
25 November 201447 Drugs That Can Be Extracted With SLE
This application note describes the extraction of 47 drugs of abuse from oral fluid matrix after sampling via Quantisal collection devices prior to UPLC-MS/MS analysis. Oral fluid collecti...
11 November 2014Crash Your Proteins in Three Steps
ISOLUTE® PLD+ plates provide extremely efficient removal of proteins and phospholipids from plasma samples using a simple 3 step procedure. Recommended operating procedure fo...
05 November 2014Improved Method Development in Food Safety
With expert support from Tyson Foods, Biotage labs has co-developed an improved method for analyzing residues of aminoglycosides in meat. This study evaluates the use of EVOLUTE® WCX s...
23 October 2014Simple Method for Screening Neuroendocrine Tumours
A simplified method for screening metanephrine and normetanephrine proves as effective as the current gold standard. It is anticipated that this time-saving and sensitive SPE-LC-ESI-MS/MS...
01 October 2014New Automated Sample Preparation System
Uppsala, Sweden, 1st October 2014 – Biotage (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces the launch of the new...
01 April 2014Analytica, Munich
Biotage is attending Analytica1-4 April 2014, Munich, Germany Introducing the latest addition to the Biotage family of sample preparation instruments! It's all happening in Hall A1 on Booth 221&n...
26 March 2011Biotage Releases Comprehensive New Catalog of Sample Preparation Products and Applications
Biotage announced the release of its new Analytical Sample Preparation Catalog. The expanded, 200-page catalog includes a range of products for Bioanalytical, Forensic, Clinical, Environmental, Agr...
10 January 2011Biotage Announces New Methods for the Extraction of Key Compounds for Clinical, Environmental and Forensic Applications
Charlotte, North Carolina USA, January 7, 2011 Biotage® (STO: BIOT), a leading supplier of tools and technology for analytical and medicinal chemistry, introduced a new series of application no...
Q&A
Why should I use positive pressure for sample preparation?
01 July 2013Question:
Why should I use positive pressure for sample preparation?
Answer:
Positive pressure generally provides improved flow characteristics, particularly for more viscous samples.
Browse more questions and answers >Can I use 6 mL (‘C’) columns on my Pressure+48?
01 July 2013Question:
Can I use 6 mL (‘C’) columns on my Pressure+48?
Answer:
Yes, in the tabless (flangeless) format.
Browse more questions and answers >INSTRUMENTS
| Part No. | Description | Product type | Pack Size | Price | ||
|
PPM-48 | Biotage® PRESSURE+ 48 Positive Pressure Manifold | Instruments | 1 | Log in for price | |
|
PPM-96 | Biotage® PRESSURE+ 96 Positive Pressure Manifold | Instruments | 1 | Log in for price | |
CONSUMABLES
| Part No. | Description | Product type | Pack Size | Price | ||
|
121-5203 | Collection Plate, 2 mL Square | Consumables | 50 | Log in for price | |
|
121-5213 | Collection Plate, 2 mL Round | Consumables | 50 | Log in for price | |
ACCESSORIES
SPARE PARTS
| Part No. | Description | Product type | Pack Size | Price | ||
| PPM-A48-GSKT | Sealing Gasket 48 position, Biotage® PRESSURE+ 48 | Spare parts | 1 | Log in for price | ||
|
PPM-A96-GSKT | Sealing Gasket 96 position, Biotage® PRESSURE+ 96 | Spare parts | 1 | Log in for price | |
|
PPM-GA | Gas Supply Adapter for all models, Biotage® PRESSURE+ | Spare parts | 1 | Log in for price | |