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Biotage® ELSD-1080
Evaporative light-scattering detector
This product has been replaced by Biotage® ELSD-A120 Detector System
| Power | 90/120V AC or 220/250V AC, 50/60 Hz 2A max |
| System control and data management | 200 mm (8”) x 415 mm (16”) x 450 mm (18”) diagonal touch screen |
| Dimensions (W x H x D) | 200 mm (8”) x 415 mm (16”) x 450 mm (18”) |
| Weight | 13 kg (28 lb) |
| Light source | LED 480 nm (Class 1 LED Product) |
| Detector | Photomultiplier tube digital signal processing |
| Temperature range | Evaporator OFF, 10 – 80 °C (1 °C increments) Nebulizer OFF, 25 – |
| Gas flow rate | 0.9 SLM to 3.25 SLM @ 25 °C with integrated controlled gas shut |
| Pressure operating range | 60 – 100 psi (4 – 6.7 bar) |
| Eluent flow rate | 0.2 – 5 mL/min |
| Analogue output | 0 – 5V FSD |
| Digital output | 24 bit digital data, 10 or 40 Hz |
| 24 bit digital data, 10 or 40 Hz | Serial (RS232) Remote Start Input Remote A/Z Contact closure TTL |
| Instrument operation | Graphical vacuum fluorescent display with keypad Ten pre-defined |
| Detector status | Standby, run |
| Safety features | Gas shut off valve, vapor and leak detection |
| Certifications | CE, CSA |
» MANUALS & USER GUIDES
Biotage® ELSD-1080 User Manual
Safety Practices and Hazards, General Information, Installation, System Description and General Operation, Routine Maintenance, and Troubleshooting.
Tags: Manuals & User Guides
ELSD-1080 - Getting started guide
ELSD-1080 (evaporative light-scattering detector) is a
universal detector designed for use with Isolera One
and Isolera Four systems when purifying compounds
with little or no UV absorption such as carbohydrates,
steroids, lipids, and terpenes
Tags: Manuals & User Guides
» PRODUCT NOTES
Isolera™ ELSD-1080 - Evaporative Light-scattering Detection
The Isolera ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera flash purification systems when purifying organic compounds that
are undetectable UV or visible light. Flash chromatography with detection and fractionation is now possible when purifying carbohydrates, steroids, lipids, terpenes and other UVtransparent compounds.
Tags: Product Notes
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Isolera™ Prime
Isolera™ Prime is a value based system which recommends appropriate cartridges and calculates the best solvent conditions and gradients for your purifications. It has solvent pumps, automated fraction collection as standard and delivers much more than just the basics. Solvent use is minimized and advanced compound detection makes sure that your purified compound is delivered at the end of the run. We belive in providing value, so Isolera Prime systems embrace ACI™, a revolutionary advancement, converting regular flash from simple purification to the fastest, greenest, and most economical way to reliably isolate pure compounds for organic synthesis. ACI offerred as standard on Isolera Prime.
Biotage® ELSD-A120
Biotage® ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable UV or visible light.
Biotage® ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable UV or visible light. Flash chromatography with detection and fractionation is now possible when purifying carbohydrates, steroids, lipids, terpenes and other UV-transparent compounds.
This product has been replaced by Biotage® ELSD-A120
Now replaced by Biotage® ELSD-A120 Detector System
Check out the ELSD-A120 Product Page »
Advanced Design
Organic compounds have different chemical and physical properties and they impact detection, even with an ELSD. Biotage ELSD-1080 provides intelligent method design which enables the chemist to independently set nebulizer and evaporator temperatures for a particular compound or compound class. Independent temperature control helps ensure that all compounds are detected.
Sub-ambient operation
Incorporated with the independent temperature control is the ability to evaporate solvents at temperatures as low as 10 °C. This is desirable when purifying highly volatile compounds.
How does ELSD work?
Sample eluting from a flash cartridge enters the ELSD where it is mixed with compressed nitrogen to nebulizer the sample (creates small droplets). The nebulizer is heated and begins to evaporate the solvent and the nitrogen pushes the sample into a heating chamber where the remaining solvent is evaporated leaving small sample particles in the nitrogen stream. While migrating through the evaporator, light is shone perpendicular to the “sample flight path” and a sensor measures how much light is coming through. Loss of light transmission is proportional to the amount of compound. This information is then relayed to the Isolera where it is then collected.
Compounds eluting from a flash cartridge enter the ELSD-1080 where they are mixed with nitrogen to nebulize the sample components creating small droplets. The nebulizer is heated and begins to evaporate the solvent and the nitrogen carries the sample into the Peltier heater where the remaining solvent is evaporated leaving small sample particles in the nitrogen stream. While migrating through the evaporator, light is shone perpendicular to the “sample flight path” and a sensor measures how many particles are present and triggering fraction collection.
- Application Areas
- Carbohydrates
- Lipids
- Steroid
- Terpenes
- Oils
- Natural Products
Features
- Flexibility – high sensitivity provides superb responses for all compounds, able to detect virtually any compound
- Sub-ambient operation – provides detection capability for highly volatile compounds with operation at temperatures as low as 10 °C up to 80 °C
- Reproducible - below 2% with reliable and accurate results
- Independent temperature controls – for both nebulizer and evaporator provides optimization capability for normal phase solvent systems
- Compact size – requires minimal bench space
- Compatible and portable – operates with other analytical HPLC systems