Learn more about the single characteristics that make Biotage® Sfär Silica HC D so special:
Biotage® is a pioneer in Flash Purification, in 1994 we were the first manufacturer of pre-packed column for flash purification. Our history and knowledge goes back much further, starting in 1969, and ranging from analytical to organic chemistry, with reliability and high quality as standard over the years.
Sfär means “Sphere” in the Swedish mother tongue of Biotage, and it has been chosen as the name for our latest columns as they contain spherical silica. Spherical silica has many advantages, the most important being its higher surface area compared to irregular silica, which translates into higher loading capacities, tighter elution bands and purer fractions.
HC stands for High Capacity and it refers both to loading capacity and performance - this derives not only from spherical silica, but also from smaller particles size (20 µ). Combined, this high surface, small particle silica improves purification performance while reducing the amount of silica and solvent required for purification. This means you can choose to run your separation with a smaller column, using less silica and less solvent, or you can increase your loading capacity and obtain a higher amount of your compound at the end.
D stands for Duo (i.e. Two), as Biotage Sfär gives you the dual possibility of liquid loading and drying loading, even though you have more than two possibilities of filling your column, they are actually six: learn more here
If you are familiar with Biotage® SNAP Ultra columns, you might have thought that that level of performance was difficult to beat, but we have achieved this with Sfär.
Check here about the comparison in terms of loading capacity between SNAP and Sfär and here for separation of Sfär versus SNAP, KP-Sil and competitive columns.
Learn more here about how particle shape and particle size can impact your chromatography load limits.