Biotage® SNAP Ultra

The term “Green Chemistry” has become a major part of the science community’s lexicon. In this application note we will look at two areas for flash chromatography: 1. Replacing chlorinated solvents with those considered more environmentally friendly. 2. Reducing solvent use and waste generation with more thoughtfully applied chromatography principles.
Tags: Application Notes

Pyrazines are a class of organic molecules often used to provide flavor to foods. They are typically synthesized but some are found in fruits and vegetables, e.g. grapes, bell peppers, peas, asparagus, beetroot, tobacco, and roasted foods. Pyrazine’s heterocyclic chemistry can yield some challenges to their purification due to the various separation kinetics between the compound and silica. Biotage SNAP Ultra.
Tags: Application Notes, English

Interview with Dr. László Kürti and Nicole Behnke at Rice University in Texas about their recent projects, how they use the Isolera™, and interesting chemistry .
Tags: Customer Cases

User report: Flash instruments. Chugai Pharmaceutical uses Biotage flash chromatography products for drug discovery research. When deciding to convert from manual open-column procedures to automated systems, they chose successive generations of Biotage products, ranging from the Flash+® packed column to the Biotage® Horizon, SP1, Isolera™ Spektra, and Isolera™ Dalton automated flash chromatography systems.
Tags: Customer Cases

Biotage®SNAP Ultra cartridges are compatible with CombiFlash® Rf Systems. As a convenience, Biotage SNAP Ultra cartridges with Luer slip connectors are available. Contact your Biotage representative for ordering information.
Tags: Manuals & User Guides

Laboratory chemical Not for therapeutic or diagnostic use
Tags: English, Material Safety Data Sheets

In medicinal chemistry, organic synthesis will generate by-products with similar chemistry to the product. Separating these impurities from the product often becomes a challenge that often only prep HPLC can achieve. In this poster, we discuss how using sample dry loading with a cation exchange scavenger media with flash chromatography improves product purity by removing many of the impurities.
Tags: Posters

New, higher default flow rates enabled by Isolera ACI systems decreases purification times compared to other systems’ and cartridges’ default flow rate settings without sacrificing separation efficiency. Incorporation of gradient optimization by converting a linear gradient to a step gradient further reduces purification time and solvent use while maintaining separation integrity for a target molecule.
Tags: Posters

SNAP Ultra cartridges increase purification throughput and product purity compared to larger standard silica cartridges.
Tags: Posters

Biotage® Selekt purification platform working in tandem with improved Biotage® Sfär columns has led to a leap forward in speed of purification and a downward trend in solvent consumption. Our team has crunched the numbers, and we’re more than happy to reveal the results.
Tags: Product Notes

Bei herkömmlichen Aufreinigungsverfahren mittels Chromatographie kommen große Mengen verhältnismäßig giftiger und teurer Lösungsmittel zum Einsatz, die sich negativ auf den ökologischen Fußabdruck von Unternehmen in der Molekularforschung auswirken. Neue Richtlinien für einen verantwortungsvolleren Umgang mit Chemikalien zwingen Unternehmen, die Umweltauswirkungen ihrer Arbeit zu reduzieren. Durch Einblicke in die Arbeitsabläufe dieser Unternehmen und neue Entwicklungen im Bereich Flash-Chromatographiesysteme und -säulen lassen sich Verbrauch und Toxizität der für die Aufreinigung eingesetzten Lösungsmittel und somit auch die Umweltbelastungen dieser Verfahren reduzieren.
Tags: Environmental, German, Product Notes, White Papers

Traditional approaches to compound purification involving chromatography utilize large volumes of relatively toxic and expensive solvents, and significantly contribute to the environmental footprint of organizations involved in molecular research. Current directives for greener chemistry have put pressure on organizations to reduce the environmental impact of their work.
Tags: Environmental, Product Notes, White Papers

Improve compound purity and flash chromatography throughput by up to 3 times while conserving solvents using Biotage® SNAP Ultra cartridges on Reveleris® Flash Chromatography Systems from Grace.
Tags: Product Notes

To save money on consumables, many chemists choose to reuse silica flash cartridges. This is true but risks purification results because chromatographic separation performance will change from run to run which reduces purification quality, especially in normal phase systems. Regardless of the cartridge brand used, repeated use of silica flash cartridges results in loss of compound resolution and therefore fraction purity.
Tags: Product Notes

With running costs and time a concern in most labs, ACI™ now promises to take users to the end point even faster and even more efficiently.
Tags: Product Notes

Precision engineered Biotage SNAP Ultra cartridges deliver double the purification capacity utilizing small particle spherical silica with an 40% increase in surface area. This proprietary silica reduces peak width and provides higher concentration fractions with less fraction volume.
Tags: English, Product Notes

Bei herkömmlichen Aufreinigungsverfahren mittels Chromatographie kommen große Mengen verhältnismäßig giftiger und teurer Lösungsmittel zum Einsatz, die sich negativ auf den ökologischen Fußabdruck von Unternehmen in der Molekularforschung auswirken. Neue Richtlinien für einen verantwortungsvolleren Umgang mit Chemikalien zwingen Unternehmen, die Umweltauswirkungen ihrer Arbeit zu reduzieren. Durch Einblicke in die Arbeitsabläufe dieser Unternehmen und neue Entwicklungen im Bereich Flash-Chromatographiesysteme und -säulen lassen sich Verbrauch und Toxizität der für die Aufreinigung eingesetzten Lösungsmittel und somit auch die Umweltbelastungen dieser Verfahren reduzieren.
Tags: Environmental, German, Product Notes, White Papers

Traditional approaches to compound purification involving chromatography utilize large volumes of relatively toxic and expensive solvents, and significantly contribute to the environmental footprint of organizations involved in molecular research. Current directives for greener chemistry have put pressure on organizations to reduce the environmental impact of their work.
Tags: Environmental, Product Notes, White Papers